• Hydroxyl radicals generated by hydrogen peroxide photolysis recondition biofilm-contaminated titanium surfaces for subsequent osteoblastic cell proliferation 

      Nakamura, Keisuke; Shirato, Midori; Tenkumo, Taichi; Kanno, Taro; Westerlund, Anna; Örtengren, Ulf Tore; Sasaki, Keiichi; Niwano, Yoshimi (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-03-18)
      Titanium dental implants have been successfully used for decades; however, some implants are affected by peri-implantitis due to bacterial infection, resulting in loss of supporting bone. This study aimed to evaluate the effect of an antimicrobial chemotherapy employing H<sub>2</sub>O<sub>2</sub> photolysis—developed to treat peri-implantitis—on biofilm-contaminated titanium surfaces in association ...
    • Photo-irradiated caffeic acid exhibits antimicrobial activity against Streptococcus mutans biofilms via hydroxyl radical formation 

      Nakamura, Keisuke; Shirato, Midori; Kanno, Taro; Lingström, Peter; Ørtengren, Ulf Thore; Niwano, Yoshimi (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-07-25)
      An antimicrobial technique based on photo-oxidation of caffeic acid (CA) has recently been developed, but its effect on biofilm-forming bacteria is unknown. The present study aimed to evaluate the effect of photo-irradiated CA against Streptococcus mutans (cariogenic bacteria) biofilm as it relates to hydroxyl radical formation. S. mutans biofilms grown on hydroxyapatite disks were immersed in CA ...
    • Surface properties of dental zirconia ceramics affected by ultrasonic scaling and low-temperature degradation 

      Nakazawa, Kosuke; Nakamura, Keisuke; Harada, Akio; Shirato, Midori; Inagaki, Ryoichi; Örtengren, Ulf; Kanno, Taro; Niwano, Yoshimi; Egusa, Hiroshi (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-09-13)
      Zirconia (3Y-TZP) dental prostheses are widely used in clinical dentistry. However, the effect of ultrasonic scaling performed as a part of professional tooth cleaning on 3Y-TZP dental prostheses, especially in conjunction with low-temperature degradation (LTD), has not been fully investigated. The present study aimed to evaluate the influence of ultrasonic scaling and LTD on the surface properties ...